Research Scientist - Protein Engineering

AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic.

We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives.

We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.

We are seeking a highly motivated Research Scientist to execute and implement sequence and structure-based in-silico tools and workflows in the areas of protein and antibody engineering.

You will interact with a diverse team, liaising between protein engineers, data scientists, software engineers, and wet-lab scientists, in a fast-paced environment.

You are someone who is able to multitask, problem-solve, think critically, and demonstrate scientific rigor, and above all, you are someone who can learn and grow with us.

How you might spend your days

• Developing, executing, and optimizing antibody bioinformatics and in-silico protein engineering tools and workflows, including sequence analysis, optimization, and liability remediation strategies
• Analyzing complex datasets from our antibody discovery and protein engineering platforms to accelerate therapeutic program development.

This includes evaluation of antibody sequence diversity and sequence risks to help identify drug candidates

• Preparing and presenting materials to educate internal and external partner teams, and communicate strategies, key findings, and implications
• Collaborating with cross-functional teams to meet project deliverables and timelines

We'd love to hear from you if

• You are excited about the opportunity to develop and execute computational antibody analysis and engineering workflows to solve real-world drug discovery problems
• You have solid experience working with protein sequences and probing sequence-structure relationships to understand and optimize protein function
• You have a PhD in Bioinformatics, Computational Biology, Structural Biology, Biochemistry, Biophysics, or a related field, or a MSc with 3+ years of related experience in a biological research setting
• You have working knowledge of antibody structure and function, and awareness of tools and techniques applicable to the molecular design and sequence optimization of antibodies
• You have excellent programming skills in Python or another programming language, and experience collaborating on a shared codebase
• You are strongly self-motivated and work independently to identify project needs and follow that up with building and implementing solutions
• You are a collaborative team player who enjoys bringing out the best in the people around you
• You can effectively communicate scientific data across different disciplines and experience levels

What we offer

AbCellera’s hiring range for this role is CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience.

In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.

Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.

About AbCellera

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives.

We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves.

A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.

We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.

To apply

Please submit your application through our website and refer to Job ID 23243 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.

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