Animal scientist Jobs in Burnaby, BC

About Us :

Process Development Scientist

About Us :

Eupraxia is a clinical-stage biotechnology company focused on developing locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. DiffuSphere™, a proprietary, polymer-based micro-sphere technology, is designed to facilitate targeted drug delivery of both existing and novel drugs. The technology is designed to support an extended duration of effect and delivery of drugs in a hyper-localized fashion, targeting only the tissues that physicians want to treat. We believe the potential for fewer adverse events may be achieved through the precision targeting and the stable and flat delivery of the active ingredient when using the DiffuSphere™ technology, versus the peaks and troughs seen with more traditional drug delivery methods. The precision of Eupraxia's DiffuSphere™ technology platform has the potential to augment and transform existing FDA-approved drugs to improve their safety, tolerability, efficacy and duration of effect. The potential uses in therapeutic areas may go beyond pain and inflammatory gastrointestinal disease, where Eupraxia currently is developing advanced treatments, also to be applicable in oncology, infectious disease and other critical disease areas.

Eupraxia's EP-104GI is currently in a Phase 1b / 2a trial, the RESOLVE trial, for the treatment of EoE. EP-104GI is administered as an injection into the esophageal wall, providing local delivery of drug. This is a unique treatment approach for EoE. Eupraxia also recently completed a Phase 2b clinical trial (SPRINGBOARD) of EP-104IAR for the treatment of pain due to knee osteoarthritis. The trial met its primary endpoint and three of the four secondary endpoints. In addition, Eupraxia is developing a pipeline of later and earlier-stage long-acting formulations. Potential pipeline indications include candidates for other inflammatory joint indications and oncology, each designed to improve on the activity and tolerability of currently approved drugs. For further details about Eupraxia, please visit the Company's website at : www.eupraxiapharma.com.

We are looking for someone who would like to work for a fast-paced, growing company that fosters a creative spirit and integrated teamwork and who is eligible to work in Canada.

Job Description :

The Process Development Scientist will be responsible for leading the development of novel viscous liquid formulations in our new British Columbia based laboratory. The successful candidate will also be responsible for the practical process scale up and ultimately involved in the detailed technology transfer to contract 3rd party manufacturing facilities. This laboratory-based position and as such it is expected that an appropriate amount of time and energy will be spent on-site versus working remotely.

Reports to : VP, CMC

Location : Vancouver, BC

Key Responsibilities :

• Perform experiments at our Laboratory site with the initial goal of developing novel viscous liquid formulations.
• Research and determine the appropriate sterilization procedures which could include sterile filtration or terminal sterilization by autoclave.
• Develop scale up processes to be suitable for transfer to a contract manufacturer.
• Submit samples for physical characterization and perform physical characterization of samples when needed. Methods may include rheology, viscoelastic analysis, NMR, thermal analysis, etc.
• Provide guidance and support in the creation and evolution of our new laboratory facilities
• Interpret and present research findings in a clear, concise manner at regular team meetings and via written reports.
• Perform other laboratory duties as needed.
• Writing appropriate sections of regulatory filings including an IND or IMPD.
• Assist with CMC department operations as requested.
• Comply with required Quality Management System procedures including maintenance of a laboratory notebook.

Additional Attributes :

Requirements :

Salary Range :   CAD$ 90,000 – 130,000 annually

Within the posted range, individual pay is determined by job-related skills, relevant experience, education and / or training. Please note that the range details above reflect the base pay only. A bonus will be available based upon performance and remaining in post for the agreed contract duration. We also have a competitive benefits package on offer.

This is an opportunity to work in a small, entrepreneurial, and highly motivating environment, with a strong emphasis on work / life balance and a supportive company culture.

How to Apply :

Please send your CV and cover letter to [email protected]

While only short-listed candidates will be notified, we thank each applicant for their submission.